These are just a couple of my favorite sick tips-
We have an extra crib mattress that we store under one of the cribs. When the girls are sick we put a sheet, a towel, and an easy to wash blanket on it and use it as the sick bed. It makes it nice for them watching tv or sleeping without the risk of having to clean the couch or big bed.
I saw this one on pinterest.
When you have medicine that needs to be taken a certain number of times per day for a certain number of days then draw a grid on the side or bottom of your medicine bottle with a permanent maker. Then mark off when it's given so you can keep track of how many doses are left. Johnny has two times a day for ten days on his bubble gum flavored amoxicillin and he started it tonight so his grid is pictures below. I just check or "x" the box when I give it to him and there isn't any guessing for when he got it last.
On the note of medicine- invest in the syringe style medicine dropper rather than the bulb. Different pharmacies give you different kinds, but I find the syringe to be easier, faster, and more precise.